Comparative Biochemistry PhD Specialized in Protein Engineering and Directed Evolution

After completing his PhD in Comparative Biochemistry at Berkeley, Paul continued his extensive work in assay development as a post-doctoral fellow at the US Dept.’s Joint Bioenergy Institute of Energy’s Deconstruction division.

He is a collaborative innovator in protein engineering, and his research, as the first author, has recently been published in PEDS.

Paul is well-read in the field of antibody engineering, including checkpoint inhibitors. His biochemistry coursework and previous experience with crystallography also give him experience with understanding structure-function relationships, including when generating novel proteins.

In addition to instructing lab techniques to undergraduates, he has extensive experience in protein purification, all major classes of chromatography, FPLC (Akta system), analytical HPLC (Dionex and Shimadzu), TFF for protein concentration, SDS-PAGE and western blot experience, antibodies, Differential Scanning Calorimetry, fluorescence-based assays, 96 and 384 well plate assays (including Biomek robot), and producing proteins cell-free and in bacterial and yeast hosts.